Show Sidebar

Episode 451: Vinay Seth Mohta – CEO & Co-Founder, Manifold

Episode 451 of The VentureFizz Podcast features Vinay Seth Mohta, CEO & Co-Founder of Manifold.

Vinay has spent his entire career at the cutting edge of complex data and systems. He cut his teeth as employee #29 at Endeca, went on to co-found Kyruus – building the healthcare industry’s leading patient access platform using machine learning and then co-founded Manifold in 2017, launching with its AI mission the very same year the foundational Transformer paper was published.

Manifold is the enterprise agent platform for life sciences. The company is on a mission to accelerate life-changing medicines to patients from early discovery to the clinic. Manifold has raised $40M to date from leading investors including Reach Capital, SilverArc Capital, Industry Ventures, TQ Ventures, and Calibrate Ventures.

In this episode, we cover:

  • Essential advice for entrepreneurs building tech startups in the highly complex, regulated healthcare industry.
  • Vinay’s background story and his formative experience at Endeca.
  • Working alongside Paul English at KAYAK and the famous “red phone” customer obsession story.
  • His journey into entrepreneurship and co-founding Kyruus using machine learning to tackle the complex matching problem between patients and physicians.
  • All the details on Manifold’s AI platform and use case examples.
  • Advice on raising follow-on rounds of funding and growth expectations in today’s venture landscape.
  • The lessons learned transitioning from Co-Founder & CTO to the Co-Founder & CEO seat.
  • And so much more!

Podcast Sponsor

First Citizens Innovation Banking serves innovative Tech, Healthcare and Life Science companies, including 50% of the Forbes 2026 Fintech 50, and 42% of the CNBC 2026 Disruptor List.

With more than 1,500 bankers and relationship advisors and $48B in loans as of Q2 2026 – First Citizens Innovation Banking delivers expert guidance, specialized products and a team that knows the innovation economy inside and out. Learn more at innovation.firstcitizens.com. Where Silicon Valley Banks.

Weekly Newsletter

Your once a week email to stay connected to all things Boston Tech.